Isle of Manos is a location mentioned in the episode Dire Straits.
Not much is known about this island except that Submarippers lived (and might still live) there.
Johann mentions that he hasn't smelled a Submaripper's odor since he traveled to the Isle of Manos.
|“||That foul odor, it's one I have not smelled for many a moon. Not since that time I ventured to the Isle of Manos across the Sea of Toglia. [src]||”|